![]() ![]() Physical organic chemists use theoretical and experimental approaches work to understand these foundational problems in organic chemistry, including classical and statistical thermodynamic calculations, quantum mechanical theory and computational chemistry, as well as experimental spectroscopy, and crystallography approaches. ![]() ![]() Such studies provide theoretical and practical frameworks to understand how changes in structure in solution or solid-state contexts impact reaction mechanism and rate for each organic reaction of interest. Physical organic chemistry is an interdisciplinary field that applies fundamental physical principles to study the relationship between the structure and reactivity of molecules.
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